TY - JOUR AU - Pavlović, Ivan AU - Omar, Eihab AU - Drobac, Milica AU - Radenković, Mirjana AU - Branković, Suzana AU - Kovačević, Nada PY - 2017/08/11 Y2 - 2024/03/28 TI - Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan JF - Archives of Biological Sciences JA - Arch Biol Sci VL - 69 IS - 3 SE - Articles DO - UR - https://www.serbiosoc.org.rs/arch/index.php/abs/article/view/540 SP - 409-415 AB - <p>The plants of genus <em>Cymbopogon</em> are well known for their use in traditional medicine and for their high content of essential oils that are widely used as flavoring agents, fragrances, cosmetics, and pharmaceuticals. Essential oils isolated from the dried stems and inflorescence of cultivated <em>Cymbopogon schoenanthus</em> (L.) Spreng. (Poaceae) collected from Khartoum state (Sudan) in two periods were studied. The results of chemical analysis of <em>C. schoenanthus </em>revealed that this plant is rich in essential oil which is a valuable source of the commercially important monoterpene, piperitone (47.7-71.5%). Other abundant constituents of the oils were intermedeol (6.1-17.3%), <em>δ</em>-2-carene (4.5-10.0%) and elemol (2.7-9.0%). The essential oil from the inflorescence was tested for spasmolytic activity using three different experimental models: against spontaneous contractions, contractions induced with acetylcholine and contractions induced with potassium chloride. The oil exhibited strong, significant and dose-dependent spasmolytic activity, indicating the possibility for further investigations of this essential oil for its medicinal purposes or application in food industry.</p><p><a href="https://doi.org/10.2298/ABS160506113P" target="_blank">https://doi.org/10.2298/ABS160506113P</a></p><div><p><strong>Received:</strong> May 6, 2016; <strong>Revised:</strong> July 6, 2016; <strong>Accepted:</strong> July 6, 2016; <strong>Published online:</strong> November 11, 2016</p><p><strong>How to cite: </strong>Pavlović I, Omar E, Drobac M, Radenković M, Branković S, Kovačević N. Chemical composition and spasmolytic activity of Cymbopogon schoenanthus (L.) Spreng. (Poaceae) essential oil from Sudan. Arch Biol Sci. 2017;69(3):409-15.</p></div><p> </p> ER -